Triple Target Achievement in Type 2 Diabetes: Synergistic Reduction in Multisystem Complications

by Prateek Chopra | July 2, 2026 | Diabetes Conferences | ADA 2026

Renal Health Focus

  • Diabetes and hypertension are major contributors to chronic kidney disease (CKD), making early identification of renal dysfunction essential.
  • This study evaluated the relationship between microalbuminuria (UACR) and renal resistive index (RRI) in individuals with diabetes, hypertension, or both.

Methods

  • A cross-sectional study enrolled 104 adults and categorized them into four groups:
    • Controls.
    • Diabetes only.
    • Hypertension only.
    • Diabetes plus hypertension.
  • UACR and RRI were assessed along with blood pressure, HbA1c, lipid profile, CRP, and eGFR.

Key Findings

  • Microalbuminuria was present in 66.7% of participants with diabetes and 60.6% of those with hypertension.
  • Among individuals with elevated UACR, 78.9% also had an elevated RRI.
  • A strong positive correlation was observed between UACR and RRI (P<0.0001).
  • The association was strongest in individuals with both diabetes and hypertension.

Clinical Implications

  • Combined assessment of UACR and RRI may improve identification of early renal dysfunction in high-risk individuals.
  • These non-invasive markers could support routine screening and risk stratification in cardiometabolic populations.

Microalbuminuria and renal resistive index were strongly correlated in individuals with diabetes and hypertension. Their combined assessment may enhance early detection of renal dysfunction and support timely intervention in high-risk patients.

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