The Natural History of Type 2 Diabetes Varies Between Clinical Subphenotypes of At-Risk Individuals

by Prateek Chopra | June 25, 2026 | Diabetes Conferences | ADA 2026 Research Objective Methods High-Risk Metabolic Clusters Study Population Changes in Insulin Sensitivity Changes in Beta-Cell Function Adiposity Trajectories Clinical Implications High-risk metabolic subphenotypes follow different pathways toward the development of T2D. While progressive insulin resistance predominates in some individuals, accelerated beta-cell deterioration drives diabetes onset in others, […]

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